WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:acylglycerol metabolic process       ID:GO:0006639
C=109; O=10; E=0.81; R=12.31; rawP=7.99e-09; adjP=3.85e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
2  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
3  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
4  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
5  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
6  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
7  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
8  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
9  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323
10  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:biological process       Name:neutral lipid metabolic process       ID:GO:0006638
C=110; O=10; E=0.82; R=12.20; rawP=8.74e-09; adjP=3.85e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
2  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
3  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
4  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
5  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
6  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
7  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
8  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
9  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323
10  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:biological process       Name:triglyceride metabolic process       ID:GO:0006641
C=104; O=10; E=0.77; R=12.91; rawP=5.05e-09; adjP=3.85e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
2  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
3  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
4  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
5  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
6  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
7  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
8  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
9  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323
10  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:biological process       Name:cellular lipid metabolic process       ID:GO:0044255
C=813; O=22; E=6.06; R=3.63; rawP=1.12e-07; adjP=3.70e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
2  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
3  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
4  ENSG00000005249 NA PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 5577 ENSG00000005249
5  ENSG00000099194 NA SCD stearoyl-CoA desaturase (delta-9-desaturase) 6319 ENSG00000099194
6  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
7  ENSG00000138413 NA IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3417 ENSG00000138413
8  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588
9  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
10  ENSG00000206527 NA PTPLB protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b 201562 ENSG00000206527
11  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
12  ENSG00000123689 NA G0S2 G0/G1switch 2 50486 ENSG00000123689
13  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
14  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
15  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
16  ENSG00000009950 NA MLXIPL MLX interacting protein-like 51085 ENSG00000009950
17  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
18  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
19  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
20  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
21  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
22  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:biological process       Name:lipid metabolic process       ID:GO:0006629
C=1141; O=26; E=8.50; R=3.06; rawP=1.95e-07; adjP=5.15e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
2  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
3  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
4  ENSG00000099194 NA SCD stearoyl-CoA desaturase (delta-9-desaturase) 6319 ENSG00000099194
5  ENSG00000005249 NA PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 5577 ENSG00000005249
6  ENSG00000182782 NA HCAR2 hydroxycarboxylic acid receptor 2 338442 ENSG00000182782
7  ENSG00000158555 NA GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 81544 ENSG00000158555
8  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
9  ENSG00000138413 NA IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3417 ENSG00000138413
10  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
11  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588
12  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
13  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
14  ENSG00000206527 NA PTPLB protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b 201562 ENSG00000206527
15  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
16  ENSG00000123689 NA G0S2 G0/G1switch 2 50486 ENSG00000123689
17  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
18  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
19  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
20  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
21  ENSG00000009950 NA MLXIPL MLX interacting protein-like 51085 ENSG00000009950
22  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
23  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
24  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
25  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
26  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:biological process       Name:regulation of lipid metabolic process       ID:GO:0019216
C=218; O=11; E=1.62; R=6.77; rawP=6.68e-07; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
2  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
3  ENSG00000186480 NA INSIG1 insulin induced gene 1 3638 ENSG00000186480
4  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
5  ENSG00000009950 NA MLXIPL MLX interacting protein-like 51085 ENSG00000009950
6  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
7  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
8  ENSG00000182782 NA HCAR2 hydroxycarboxylic acid receptor 2 338442 ENSG00000182782
9  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
10  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
11  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092


Database:biological process       Name:lipid localization       ID:GO:0010876
C=236; O=11; E=1.76; R=6.26; rawP=1.46e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
2  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
3  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
4  ENSG00000123612 NA ACVR1C activin A receptor, type IC 130399 ENSG00000123612
5  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
6  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
7  ENSG00000106484 NA MEST mesoderm specific transcript homolog (mouse) 4232 ENSG00000106484
8  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
9  ENSG00000197696 NA NMB neuromedin B 4828 ENSG00000197696
10  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
11  ENSG00000168398 NA BDKRB2 bradykinin receptor B2 624 ENSG00000168398


Database:biological process       Name:triglyceride biosynthetic process       ID:GO:0019432
C=56; O=6; E=0.42; R=14.38; rawP=3.57e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
2  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
3  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
4  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
5  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
6  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:biological process       Name:acylglycerol biosynthetic process       ID:GO:0046463
C=58; O=6; E=0.43; R=13.88; rawP=4.40e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000119927 NA GPAM glycerol-3-phosphate acyltransferase, mitochondrial 57678 ENSG00000119927
2  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
3  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
4  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
5  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
6  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:biological process       Name:lipid storage       ID:GO:0019915
C=50; O=6; E=0.37; R=16.11; rawP=1.81e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
2  ENSG00000106484 NA MEST mesoderm specific transcript homolog (mouse) 4232 ENSG00000106484
3  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
4  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
5  ENSG00000123612 NA ACVR1C activin A receptor, type IC 130399 ENSG00000123612
6  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282


Database:molecular function       Name:carboxylic acid binding       ID:GO:0031406
C=195; O=8; E=1.37; R=5.86; rawP=6.74e-05; adjP=0.0123
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100504 NA PYGL phosphorylase, glycogen, liver 5836 ENSG00000100504
2  ENSG00000135917 NA SLC19A3 solute carrier family 19, member 3 80704 ENSG00000135917
3  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
4  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
5  ENSG00000008394 NA MGST1 microsomal glutathione S-transferase 1 4257 ENSG00000008394
6  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
7  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
8  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:molecular function       Name:carbohydrate derivative binding       ID:GO:0097367
C=189; O=7; E=1.32; R=5.29; rawP=0.0004; adjP=0.0182
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000142949 NA PTPRF protein tyrosine phosphatase, receptor type, F 5792 ENSG00000142949
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571
3  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
4  ENSG00000064886 NA CHI3L2 chitinase 3-like 2 1117 ENSG00000064886
5  ENSG00000012223 NA LTF lactotransferrin 4057 ENSG00000012223
6  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
7  ENSG00000103196 NA CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 83716 ENSG00000103196


Database:molecular function       Name:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity       ID:GO:0004879
C=48; O=4; E=0.34; R=11.90; rawP=0.0003; adjP=0.0182
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151090 NA THRB thyroid hormone receptor, beta 7068 ENSG00000151090
2  ENSG00000050628 NA PTGER3 prostaglandin E receptor 3 (subtype EP3) 5733 ENSG00000050628
3  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
4  ENSG00000175745 NA NR2F1 nuclear receptor subfamily 2, group F, member 1 7025 ENSG00000175745


Database:molecular function       Name:6-phosphofructo-2-kinase activity       ID:GO:0003873
C=4; O=2; E=0.03; R=71.42; rawP=0.0003; adjP=0.0182
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571


Database:molecular function       Name:fructose-2,6-bisphosphate 2-phosphatase activity       ID:GO:0004331
C=6; O=2; E=0.04; R=47.61; rawP=0.0007; adjP=0.0212
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571


Database:molecular function       Name:receptor binding       ID:GO:0005102
C=1211; O=19; E=8.48; R=2.24; rawP=0.0007; adjP=0.0212
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166923 NA GREM1 gremlin 1 26585 ENSG00000166923
2  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
3  ENSG00000145423 NA SFRP2 secreted frizzled-related protein 2 6423 ENSG00000145423
4  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
5  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
6  ENSG00000160307 NA S100B S100 calcium binding protein B 6285 ENSG00000160307
7  ENSG00000173432 NA SAA1 serum amyloid A1 6288 ENSG00000173432
8  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
9  ENSG00000197696 NA NMB neuromedin B 4828 ENSG00000197696
10  ENSG00000138413 NA IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3417 ENSG00000138413
11  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
12  ENSG00000142949 NA PTPRF protein tyrosine phosphatase, receptor type, F 5792 ENSG00000142949
13  ENSG00000135144 NA DTX1 deltex homolog 1 (Drosophila) 1840 ENSG00000135144
14  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
15  ENSG00000172037 NA LAMB2 laminin, beta 2 (laminin S) 3913 ENSG00000172037
16  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
17  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
18  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
19  ENSG00000168398 NA BDKRB2 bradykinin receptor B2 624 ENSG00000168398


Database:molecular function       Name:identical protein binding       ID:GO:0042802
C=863; O=15; E=6.04; R=2.48; rawP=0.0010; adjP=0.0227
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571
3  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
4  ENSG00000134602 NA MST4 serine/threonine protein kinase MST4 51765 ENSG00000134602
5  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
6  ENSG00000100504 NA PYGL phosphorylase, glycogen, liver 5836 ENSG00000100504
7  ENSG00000160307 NA S100B S100 calcium binding protein B 6285 ENSG00000160307
8  ENSG00000009950 NA MLXIPL MLX interacting protein-like 51085 ENSG00000009950
9  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
10  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
11  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
12  ENSG00000138413 NA IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3417 ENSG00000138413
13  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
14  ENSG00000008394 NA MGST1 microsomal glutathione S-transferase 1 4257 ENSG00000008394
15  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:molecular function       Name:phosphofructokinase activity       ID:GO:0008443
C=7; O=2; E=0.05; R=40.81; rawP=0.0010; adjP=0.0227
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571


Database:molecular function       Name:prostaglandin receptor activity       ID:GO:0004955
C=11; O=2; E=0.08; R=25.97; rawP=0.0026; adjP=0.0332
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000050628 NA PTGER3 prostaglandin E receptor 3 (subtype EP3) 5733 ENSG00000050628
2  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170


Database:molecular function       Name:icosanoid receptor activity       ID:GO:0004953
C=12; O=2; E=0.08; R=23.81; rawP=0.0031; adjP=0.0332
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000050628 NA PTGER3 prostaglandin E receptor 3 (subtype EP3) 5733 ENSG00000050628
2  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170


Database:cellular component       Name:lipid particle       ID:GO:0005811
C=42; O=7; E=0.30; R=23.68; rawP=1.58e-08; adjP=2.01e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176194 NA CIDEA cell death-inducing DFFA-like effector a 1149 ENSG00000176194
2  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
3  ENSG00000187288 NA CIDEC cell death-inducing DFFA-like effector c 63924 ENSG00000187288
4  ENSG00000123689 NA G0S2 G0/G1switch 2 50486 ENSG00000123689
5  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
6  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
7  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:cellular component       Name:extracellular region       ID:GO:0005576
C=2140; O=30; E=15.06; R=1.99; rawP=0.0001; adjP=0.0063
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166923 NA GREM1 gremlin 1 26585 ENSG00000166923
2  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
3  ENSG00000145423 NA SFRP2 secreted frizzled-related protein 2 6423 ENSG00000145423
4  ENSG00000186458 NA DEFB132 defensin, beta 132 400830 ENSG00000186458
5  ENSG00000088882 NA CPXM1 carboxypeptidase X (M14 family), member 1 56265 ENSG00000088882
6  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
7  ENSG00000174807 NA CD248 CD248 molecule, endosialin 57124 ENSG00000174807
8  ENSG00000160307 NA S100B S100 calcium binding protein B 6285 ENSG00000160307
9  ENSG00000148848 NA ADAM12 ADAM metallopeptidase domain 12 8038 ENSG00000148848
10  ENSG00000173432 NA SAA1 serum amyloid A1 6288 ENSG00000173432
11  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
12  ENSG00000197696 NA NMB neuromedin B 4828 ENSG00000197696
13  ENSG00000091513 NA TF transferrin 7018 ENSG00000091513
14  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
15  ENSG00000012223 NA LTF lactotransferrin 4057 ENSG00000012223
16  ENSG00000103196 NA CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 83716 ENSG00000103196
17  ENSG00000182704 NA TSKU tsukushi small leucine rich proteoglycan homolog (Xenopus laevis) 25987 ENSG00000182704
18  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
19  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
20  ENSG00000064886 NA CHI3L2 chitinase 3-like 2 1117 ENSG00000064886
21  ENSG00000108950 NA FAM20A family with sequence similarity 20, member A 54757 ENSG00000108950
22  ENSG00000219438 NA FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 25817 ENSG00000219438
23  ENSG00000172037 NA LAMB2 laminin, beta 2 (laminin S) 3913 ENSG00000172037
24  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
25  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
26  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
27  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
28  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092
29  ENSG00000130173 NA C19orf80 chromosome 19 open reading frame 80 55908 ENSG00000130173
30  ENSG00000224420 NA C19orf76 chromosome 19 open reading frame 76 199800 ENSG00000224420


Database:cellular component       Name:cytoplasmic membrane-bounded vesicle lumen       ID:GO:0060205
C=54; O=4; E=0.38; R=10.53; rawP=0.0006; adjP=0.0191
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
2  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
3  ENSG00000012223 NA LTF lactotransferrin 4057 ENSG00000012223
4  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192


Database:cellular component       Name:vesicle lumen       ID:GO:0031983
C=56; O=4; E=0.39; R=10.15; rawP=0.0006; adjP=0.0191
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
2  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
3  ENSG00000012223 NA LTF lactotransferrin 4057 ENSG00000012223
4  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192


Database:cellular component       Name:secretory granule       ID:GO:0030141
C=257; O=7; E=1.81; R=3.87; rawP=0.0023; adjP=0.0584
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198576 NA ARC activity-regulated cytoskeleton-associated protein 23237 ENSG00000198576
2  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
3  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
4  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
5  ENSG00000091513 NA TF transferrin 7018 ENSG00000091513
6  ENSG00000012223 NA LTF lactotransferrin 4057 ENSG00000012223
7  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192


Database:cellular component       Name:platelet alpha granule lumen       ID:GO:0031093
C=47; O=3; E=0.33; R=9.07; rawP=0.0044; adjP=0.0931
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
2  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
3  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192


Database:cellular component       Name:secretory granule lumen       ID:GO:0034774
C=50; O=3; E=0.35; R=8.53; rawP=0.0052; adjP=0.0943
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
2  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
3  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192


Database:cellular component       Name:cytosol       ID:GO:0005829
C=2372; O=27; E=16.69; R=1.62; rawP=0.0070; adjP=0.1016
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196565 NA HBG2 hemoglobin, gamma G 3048 ENSG00000196565
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571
3  ENSG00000151365 NA THRSP thyroid hormone responsive 7069 ENSG00000151365
4  ENSG00000056998 NA GYG2 glycogenin 2 8908 ENSG00000056998
5  ENSG00000123360 NA PDE1B phosphodiesterase 1B, calmodulin-dependent 5153 ENSG00000123360
6  ENSG00000072422 NA RHOBTB1 Rho-related BTB domain containing 1 9886 ENSG00000072422
7  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
8  ENSG00000169710 NA FASN fatty acid synthase 2194 ENSG00000169710
9  ENSG00000100504 NA PYGL phosphorylase, glycogen, liver 5836 ENSG00000100504
10  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
11  ENSG00000005249 NA PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 5577 ENSG00000005249
12  ENSG00000006715 NA VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 27072 ENSG00000006715
13  ENSG00000147251 NA DOCK11 dedicator of cytokinesis 11 139818 ENSG00000147251
14  ENSG00000187288 NA CIDEC cell death-inducing DFFA-like effector c 63924 ENSG00000187288
15  ENSG00000141161 NA UNC45B unc-45 homolog B (C. elegans) 146862 ENSG00000141161
16  ENSG00000092621 NA PHGDH phosphoglycerate dehydrogenase 26227 ENSG00000092621
17  ENSG00000138413 NA IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3417 ENSG00000138413
18  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192
19  ENSG00000164879 NA CA3 carbonic anhydrase III, muscle specific 761 ENSG00000164879
20  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588
21  ENSG00000131771 NA PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 84152 ENSG00000131771
22  ENSG00000134602 NA MST4 serine/threonine protein kinase MST4 51765 ENSG00000134602
23  ENSG00000169228 NA RAB24 RAB24, member RAS oncogene family 53917 ENSG00000169228
24  ENSG00000135144 NA DTX1 deltex homolog 1 (Drosophila) 1840 ENSG00000135144
25  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
26  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
27  ENSG00000009950 NA MLXIPL MLX interacting protein-like 51085 ENSG00000009950


Database:cellular component       Name:extracellular space       ID:GO:0005615
C=856; O=13; E=6.02; R=2.16; rawP=0.0072; adjP=0.1016
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
2  ENSG00000166923 NA GREM1 gremlin 1 26585 ENSG00000166923
3  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
4  ENSG00000145423 NA SFRP2 secreted frizzled-related protein 2 6423 ENSG00000145423
5  ENSG00000064886 NA CHI3L2 chitinase 3-like 2 1117 ENSG00000064886
6  ENSG00000088882 NA CPXM1 carboxypeptidase X (M14 family), member 1 56265 ENSG00000088882
7  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
8  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
9  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
10  ENSG00000174697 NA LEP leptin 3952 ENSG00000174697
11  ENSG00000173432 NA SAA1 serum amyloid A1 6288 ENSG00000173432
12  ENSG00000118137 NA APOA1 apolipoprotein A-I 335 ENSG00000118137
13  ENSG00000181092 NA ADIPOQ adiponectin, C1Q and collagen domain containing 9370 ENSG00000181092


Database:cellular component       Name:platelet alpha granule       ID:GO:0031091
C=60; O=3; E=0.42; R=7.11; rawP=0.0087; adjP=0.1105
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138722 NA MMRN1 multimerin 1 22915 ENSG00000138722
2  ENSG00000100311 NA PDGFB platelet-derived growth factor beta polypeptide 5155 ENSG00000100311
3  ENSG00000142192 NA APP amyloid beta (A4) precursor protein 351 ENSG00000142192




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).